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| Revolutionize iPS Spheroid Culture with ABLE 3D Magnetic Stir Bioreactor System |
In the realm of stem cell research, the need for efficient, cost-effective, and scalable solutions is paramount. AMSBIO introduces the ABLE 3D Magnetic Stir and Disposable Bioreactor System, a game-changing tool for lab-scale induced pluripotent stem (iPS) cell spheroid culture production.
Simulating the natural structure of embryoid bodies formed by embryonic stem cells, growing iPS cells in 3D spheroid suspension culture has long been a goal for researchers. The ABLE 3D Bioreactor steps in as a user-friendly and economical solution that ensures high yield, viability, and efficiency in expanding human iPS stem cells and promoting their differentiation.
Constructed from high-density polycarbonate, this Bioreactor is designed to seamlessly accommodate iPS stem cell cultivation. It arrives ready-to-use for non-adherent cell growth, eliminating the need for costly extracellular matrix (ECM) proteins to coat plasticware. What sets it apart is its delta-wing-shaped impeller, featuring a magnet on each blade. This innovative design creates low shear agitation through laminar flow, facilitating the development of uniform 200-300 μm spheroid cell clusters.
The ABLE 3D Bioreactor is a standout because it employs disposable vessels for cell culture or production, with each 30 mL vessel capable of yielding up to 5 × 10^7 cells. This is equivalent to the cell output from ten 10 cm culture dishes or ten 6-well plates, making it an incredibly efficient and scalable option.
One of the key advantages of this system is its seamless integration with StemFit media, a chemically defined stem cell culture medium. With the ABLE 3D Bioreactor, researchers can efficiently maintain induced pluripotent stem cells (iPSCs) and embryonic stem cells (ESCs) without the need for feeder cells. By using iMatrix-511-coated plates in conjunction with StemFit media, human iPSCs can be readily harvested, dissociated into single cells, and seamlessly transitioned into the ABLE 3D Bioreactor system for large-scale and efficient iPSC spheroid culture.
This revolutionary system opens new doors in the world of iPS spheroid culture, offering an affordable, scalable, and efficient solution for researchers looking to advance their stem cell work. Whether you're focused on iPSCs, ESCs, or the differentiation of pluripotent stem cells, the ABLE 3D Magnetic Stir Bioreactor System is poised to transform your research capabilities.
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